Howard J. Halpern, MD, PhD, specializes in medical imaging techniques. He is an expert in very low frequency-imaging-electron paramagnetic resonance (VLF-I-EPR). This technique enables measurement of changes in oxygen content in tumor tissues--a key determinant of response to radiation therapy.
Dr. Halpern is the co-author of a textbook on free radical biology. He serves as the principal investigator for the Oversight Committee for the Laboratory Training of Radiation Oncology Residents.
University of Wisconsin
Madison, Wisconsin
PhD - High Energy Physics
1976
University of Miami
Miami, Florida
MD - Medicine
061980
Directional TV algorithm for image reconstruction from sparse-view projections in EPR imaging.
Directional TV algorithm for image reconstruction from sparse-view projections in EPR imaging. Phys Med Biol. 2024 May 30; 69(11).
PMID: 38729205
Validation of the design of a high-sensitivity and high-resolution PET system for a preclinical PET/EPR hybrid scanner.
Validation of the design of a high-sensitivity and high-resolution PET system for a preclinical PET/EPR hybrid scanner. Nucl Instrum Methods Phys Res A. 2024 Jun; 1063.
PMID: 38736647
Sensing and Imaging Molecular Oxygen in Mammals with Spin Lattice Relaxation Electron Paramagnetic Resonance.
Sensing and Imaging Molecular Oxygen in Mammals with Spin Lattice Relaxation Electron Paramagnetic Resonance. Mol Imaging Biol. 2024 Jun; 26(3):373-381.
PMID: 38548994
Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI.
Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI. J Magn Reson. 2024 Apr; 361:107654.
PMID: 38492546
Directional TV algorithm for fast EPR imaging.
Directional TV algorithm for fast EPR imaging. J Magn Reson. 2024 Apr; 361:107652.
PMID: 38457937
Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models.
Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models. Front Med (Lausanne). 2023; 10:1339872.
PMID: 38116039
Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models.
Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models. Front Med (Lausanne). 2023; 10:1269689.
PMID: 37904839
A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module.
A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module. IEEE Trans Radiat Plasma Med Sci. 2023 Nov; 7(8):794-801.
PMID: 37981977
Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance.
Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance. Antioxid Redox Signal. 2024 May; 40(13-15):850-862.
PMID: 36680741
A Simple but Universal Fully Linearized ADMM Algorithm for Optimization Based Image Reconstruction.
A Simple but Universal Fully Linearized ADMM Algorithm for Optimization Based Image Reconstruction. Res Sq. 2023 Apr 28.
PMID: 37162853